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井上 大輔 井上 大輔
INOUE Daisuke
Assistant Professor
INOUE Daisuke
Department
Department of Pharmacy
Laboratory
Molecular Pharmaceutics Laboratory
Field of Study
Chemistry

History

Graduate School/University, etc.

2007 Graduated from School of Pharmacy, Shujitsu University 2009 Completed First Term Doctoral Course in Pharmaceutical Sciences, Division of Pharmaceutical Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University 2013 Completed Second Term Doctoral Course in Pharmaceutical Sciences, Division of Pharmaceutical Sciences, Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama University

研究者になったきっかけ

Why I Became a Researcher

When I was in high school, I witnessed a close relative suffering from illness and the side effects of their medicine. This made me wonder if it was possible to develop pharmaceutical products that were effective without causing harmful side effects, causing me to have an interest in pharmacy. After that, I wanted to be a researcher involved in medicine, and I went into a school of pharmacy in university. When I was a student, in pharmaceutics, I learned that it was possible to control the behavior of ingested drugs in vivo through pharmacokinetics, DDS, and formulation research, and that research could lead to more effective and safer drug development. Knowing this made me want to know more about pharmaceutics. After that, while pursuing the research tasks of evaluating drug absorption after nasal administration and developing a model for predicting absorption, I became fascinated by the originality and development potential of these tasks, and came to know the joy of research.

Research Information

Research Area and Theme

Pharmacokinetic Control by Kinetic Modeling of Drug Absorption and Its Application to Formulation Research

I am conducting research to enable the prediction of drug absorption development by constructing a pharmacokinetic model based on the pharmacokinetic analysis data of a drug after administration and to lead to the development of unprecedented, novel formulation through deployment in formulation research.

Thoughts on Research Theme

Currently, for example, in central nervous system diseases such as dementia and neuropsychiatric disorders, the need for pharmaceutical products is growing along with a rapid increase in the number of patients, but at present, it is difficult to develop therapeutics for these diseases. One of the reasons for this is that it is not possible to deliver a sufficient amount of a drug to central regions, resulting in ineffectiveness. And so, in the development of pharmaceuticals, it is important to have a firm understanding of drug absorption and tissue transportability in vivo, and to predict and control pharmacokinetics. To address this, if a kinetic model of drug absorption and tissue transportation is created, and there is an evaluation method that can predict these with high accuracy, I believe that it will be possible to conduct research to make more effective therapeutic drug formulations, and to deploy this research for the development of effective and safe new drugs. Through this basic research, I hope to provide new knowledge that does not exist in the world and contribute to society at large.

Message to Students

井上 大輔 学生へのメッセージ 井上 大輔 学生へのメッセージ

I would like to support students so that they can experience the joy of research and smoothly continue their daily research activities

With research activities, you can acquire the ability to solve problems and perform research by investigating research tasks and drafting experiment plans on your own. The knowledge that you learn and the skills acquired through research activities will become skills that are useful for you not only as researchers in the future, but also as active pharmacists in the medical field. In research, it is often difficult to solve issues alone. And so, I would like to support students so that they can experience the joy of research and smoothly continue their daily research activities.

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